If playing as Cain, he will never be able to shoot the blood laser.
Spider's Bite - Laser has a chance to slow enemies down for 2.5 seconds.
The Common Cold - Laser has chance for poisoning enemies for 2.5 seconds.Actual damage bonus is ( bonus from Polyphemus) * 3, so overall bonus decreases if stacked with The Inner Eye/Mutant Spider.Polyphemus - Brimstone charges more slowly, but damage is increased exponentially (enough to one or two-shot most bosses.).Sacred Heart - Damage of the laser is greatly increased, with a slightly longer charge time.These damage increases do not stack with each other.The Inner Eye, Mutant Spider, IPECAC - Brimstone charges slower (3-4 sec) but has tripled damage.
#BINDING OF ISAAC CONSOLE COMMANDS STAGE HUSH FULL#
Charging before entering a room will result in the appearance of a full charge, but the fired shot will not damage enemies. Chocolate Milk - Allows partial charge doing damage in relation to charging time, but Brimstone will charge slower than it shows (e.g.Shoop Da Whoop! - This active will take a massive damage decrease when paired with Brimstone.Mom's Knife, Epic Fetus - Overrides Brimstone.Fetus - Overridden by Brimstone, with no stat change. This item has 75% lower chance to appear in Hard Mode.Despite common belief, an increased tears stat does not reduce the charge up time of Brimstone.If the player has an item like Transcendence, Isaac will get wings instead of losing his body.An increased damage stat does increase Brimstone's damage.Getting hit while charging will reset the charge.Attempting to fire the beam before it is fully charged will cancel the charge.Even if Isaac have not finished charging Brimstone when he'll pass through a door, it is always fully charged once a new room is entered if the fire button is still being held. It is possible to charge before entering a room so that the first shot can be fired immediately. Each laser is emitted for about one second and hits twice, so it is possible to destroy some two-stage enemies in one shot ( Globins and Hives along with the flies they spawn on death), or to strafe the shot over multiple enemies. It can only be fired after a short charge-up period (approximately 1-2 seconds until Isaac's head begins flashing red). It also changes tears to a chargeable laser that pierces all objects in its path (including enemies, environmental hazards and walls). Picking up Brimstone will multiply Isaac's current damage by 3. Isaac appears demonic with large curved horns and an angry expression.